Human Reproduction Update first published in 1995 aims to provide invited comprehensive authoritative up-to-date critical and balanced reviews covering all areas of human reproduction including reproductive physiology and pathology endocrinology andrology gonad function gametogenesis fertilization embryo development implantation pregnancy genetics genetic diagnosis oncology infectious disease surgery contraception infertility treatment psychology and counselling ethics and social issues. These papers are peer-reviewed to the highest editorial and scientific standards. Human Reproduction Update is published on behalf of the European Society of Human Reproduction and Embryology (ESHRE).